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slobber2

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Reply with quote  #251 
HI
I was helping my Friend ,look for a Stud . And of course Cystinuria testing is onHis List .

I havent really seen a whole, lot of Studs with , Cystinuria testing being shown.


Do some just dont put it up ? Or are some just not thinking its a big deal ??

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jkruer01

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Reply with quote  #252 
I think the majority are not testing for it.

Jeremy

SteveOifer

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Reply with quote  #253 
Bulldog, bullmastiff, newf, saint, DDB, bloodhound, dane, etc., etc., etc.

It's no wonder why the newf gene was an easy find compared to the "mastiff" gene!

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"Above all, a uniform type should be aimed at by breeders and uniformity of type can only exist in a proportionate ratio in the purity and distinctiveness in any breed"!.........M. Moore
"If breeds did not adhere to a specific shape, form, and colour range, or if breeders disregarded this blueprint, the breed would degenerate to the point that it would hardly resemble the breed at all. Selective breeding does not just create breeds- it preserves them as well. Breeding purebred dogs inherently means accepting limitations on your freedom to just breed anything"...Catherine McMillan
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TEST YOUR DOGS!
jkruer01

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Reply with quote  #254 
There are at least 3 forms of Cystinuria in Humans (so I have been told).  There could easily be more than one form in Mastiffs as well.

Jeremy

Janine

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Reply with quote  #255 
Probably a stupid question, but if it came down from the newf, wouldn't the gene be the same?  That should make it easier I would think.
Janine.
DanH

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Reply with quote  #256 

This is probably a dumb question, but when a person has kidney stones is this a human form of Cystinuria?

jkruer01

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Reply with quote  #257 
They already tested Mastiffs to see if it was the same gene as in Newfs...and unfortunately it is not the same.  I wish it were because then we would have a DNA test available.

Kidney stones are created from calcium (I think) not cystine so it is something different.  Just like in dogs, there are multiple types of stones that can form in the digestive tract.  Cystinuria stones are formed from cystine.  If the stone is formed by another mineral then it is something different than cystinuria.

Hope that helps,

Jeremy

slobber2

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Reply with quote  #258 

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Ya now ,i was just talking to someone last nite ,about that.
She was saying Maybe we should go by how much Cystine .
The Dog is producing , maybe some get kidney disease.

And maybe some get stones ,and then some just stay the same ? 

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Old post Today at 05:23 PM #254

There are at least 3 forms of Cystinuria in Humans (so I have been told).  There could easily be more than one form in Mastiffs as well.

Jeremy

slobber2

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Reply with quote  #259 
I think the majority are not testing for it.

Jeremy


Hi
Yes i think your right :>)

But maybe this put a fire under everyone :>)

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jkruer01

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Reply with quote  #260 
Quote:
why would anyone use a stud dog that had not been tested for cystinuria?


Well, because the majority of them haven't been tested. Of the ones that have been tested a lot have only been tested once so even those results don't mean anything.  In an ideal world everyone would test for Cystinuria and be honest about the results.  Until then though people have to settle for what is available.

Thanks,

Jeremy

jkruer01

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Reply with quote  #261 
Quote:
Maybe we should go by how much Cystine .
The Dog is producing


I think this is what UPenn does.  Up to a certain level of Cystine the reports are reported as "Negative".  However, once it gets over a certain level then it is reported "Positive".

Jeremy

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